MYD88 Mouse Monoclonal Antibody [Clone ID: OTI2B2]

CAT#: TA502117

MYD88 mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)


 Product Datasheet for 'TA502117'

Need it in bulk or conjugated?
Get a free quote

USD 350.00


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI2B2
Applications WB, IHC, IF, FC
Recommend Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
Isotype IgG2a
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 33.1 kDa
Gene Name myeloid differentiation primary response 88
Background This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
Synonyms MYD88D
Reference Data
Protein Families Druggable Genome
Protein Pathways Apoptosis, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)