PANK2 Mouse Monoclonal Antibody [Clone ID: OTI3H9]

CAT#: TA501321

anti-PANK2 mouse monoclonal antibody, clone OTI3H9 (formerly 3H9)

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 Product Datasheet for 'TA501321'

USD 379.00

In Stock

    • 100 ul


Product Data
Clone Name OTI3H9
Applications WB, IHC, IF, FC
Recommend Dilution WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Dog, Rat, Monkey
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PANK2(NP_705902) produced in HEK293T cell.
Isotype IgG2a
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 59.1 kDa
Gene Name pantothenate kinase 2
Background This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq].
Synonyms C20orf48|HARP|HSS|NBIA1|PKAN
Reference Data
Protein Families Druggable Genome
Protein Pathways Pantothenate and CoA biosynthesis, Metabolic pathways
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