PANK2 Mouse Monoclonal Antibody [Clone ID: OTI3H9]

CAT#: TA501321

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Anti-PANK2 mouse monoclonal antibody, clone OTI3H9 (formerly 3H9)



  View other "OTI3H9" antibodies (4)

Special Offer: Try sample size of this antibody at $99/€99. Use code “TrueSample”.

USD 446.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI3H9
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Monkey, Mouse, Rat, Dog
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PANK2(NP_705902) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 59.1 kDa
Gene Name pantothenate kinase 2
Background This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq]
Synonyms C20orf48; HARP; HSS; NBIA1; PKAN
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Pantothenate and CoA biosynthesis

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