FKBP12 (FKBP1A) Mouse Monoclonal Antibody [Clone ID: OTI3B3]

CAT#: TA500557

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FKBP1A (FKBP12) mouse monoclonal antibody, clone OTI3B3 (formerly 3B3)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



  View other "OTI3B3" antibodies (4)

USD 447.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
Recombinant protein of human FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12B
    • 100 ug

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Transient overexpression lysate of FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12B
    • 100 ug

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications

Product Data
Clone Name OTI3B3
Applications FC, IHC, WB
Recommended Dilution WB: 1:200 - 1:1000, IHC 1:150, FLOW 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FKBP1A (NP_000792) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration Lot dependent
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 11.8 kDa
Gene Name FKBP prolyl isomerase 1A
Background The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq]
Synonyms FKBP-1A; FKBP-12; FKBP1; FKBP12; FKBP12-Exip3; FKBP12C; PKC12; PKCI2; PPIASE; rotamase
Reference Data
Protein Families Druggable Genome

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