Cytochrome C Oxidase subunit VIb (COX6B1) Rabbit Polyclonal Antibody

CAT#: TA308205

Rabbit Polyclonal antibody to COX6B1 (cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous))

Product Images

Sample (30 ug of whole cell lysate). A: Hep G2. 15% SDS PAGE. COX6B1 antibody. TA308205 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded BCC3 xenograft, using COX6B1 (TA308205) antibody at 1:100 dilution.

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  COX6B1 antibody [N2C3] detects COX6B1 protein at mitochondria by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: COX6B1 protein stained by COX6B1 antibody [N2C3] (TA308205) diluted at 1:500. Blue:

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Bovine, Rhesus Monkey, X. tropicalis)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 23 and 86 of COX6B1 (Uniprot ID#P14854)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 10 kDa
• Gene Name: cytochrome c oxidase subunit 6B1
• Database Link:
  NP_001854
  Entrez Gene 1340 Human
  UniProt ID P14854
• Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq]
• Synonyms: COX6B; COXG; COXVIb1
• Note: Seq homology of immunogen across species: Xenopus Tropicalis (86%), Rhesus Monkey (100%), Bovine (86%)

Reference Data

• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease