CD55 Mouse Monoclonal Antibody [Clone ID: MEM-118]

USD 260.00

2 Weeks

    • 100 ug

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Product Data
Clone Name MEM-118
Applications FC
Recommend Dilution FC:10 ug/ml,IHC (paraffin sections): 10 ug/ml
Reactivity Human, Non-Human Primates
Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen HPB-ALL human T cell line.
Formulation Phosphate buffered saline (PBS) containing 15 mM Sodium Azide as presrevative.
Gene Name CD55 molecule (Cromer blood group)
Background CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Synonyms CR; CROM; DAF; TC
Reference Data
Protein Families Druggable Genome
Protein Pathways Complement and coagulation cascades, Hematopoietic cell lineage, Viral myocarditis

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