TLR4 Mouse Monoclonal Antibody [Clone ID: HTA125]

CAT#: SM1677R

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TLR4 mouse monoclonal antibody, clone HTA125, PE



USD 550.00


Availability*
5 Days

Size
    • 100 Tests


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Specifications

Product Data
Clone Name HTA125
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat antibody to label 106 cells or 100 µl whole blood.
Reactivity Canine, Guinea Pig, Human, Monkey, Porcine
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Ba/F3 cell line expressing TLR4 (CD284).
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity This antibody recognises the Toll like receptor 4 (TLR4) cell surface antigen.
This antibody has been demonstrated to block activation of monocytes with LPS. We recommend the use of SM1677LE for this purpose.
Formulation PBS
Label: PE
State: Lyophilized purified IgG fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA and 5% Sucrose
Preservative: 0.09% Sodium Azide
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with 1.0 ml distilled water.
Purification Affinity Chromatography on Protein G
Conjugation PE
Storage

Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.

Stability Shelf life: one year from despatch.

Background TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.
Synonyms Toll-like receptor 4
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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