MADCAM1 Mouse Monoclonal Antibody [Clone ID: OTI1B7]

CAT#: CF507035

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Carrier-free (BSA/glycerol-free) MADCAM1 mouse monoclonal antibody, clone OTI1B7 (formerly 1B7)



  View other "OTI1B7" antibodies (4)

USD 600.00


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Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI1B7
Applications WB
Recommended Dilution WB 1:400~4000
Reactivities Human, Mouse, Rat, Dog
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MADCAM1(NP_570116) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 38.3 kDa
Gene Name Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, mRNA.
Background The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Synonyms MACAM1
Reference Data
Protein Pathways Cell adhesion molecules (CAMs)

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