IKK gamma (IKBKG) pSer376 Rabbit Polyclonal Antibody
IKK gamma (IKBKG) pSer376 rabbit polyclonal antibody, Aff - Purified
|Recommended Dilution||Immunohistochemistry on paraffin sections: 1:50~1:100 .|
|Immunogen||Peptide sequence around phosphorylation site of Serine 376(Y-L-S(p)-S-P) derived from Human IKK-γ (KLH-conjugated)|
|Specificity||The antibody detects endogenous levels of IKK-γ only when phosphorylated at serine 376.|
|Formulation||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
|Purification||Affinity chromatography using epitope-specific peptide|
|Storage||Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Predicted Protein Size||48 kDa|
|Background||Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation.|
|Synonyms||FIP3, FIP-3, IKKAP1, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.