LOX (Center) Rabbit Polyclonal Antibody

CAT#: AP52513PU-N

LOX (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Lysyl oxidase Antibody (Center) in MDA-MB468 cell line lysates (35ug/lane). LOX (arrow) was detected using the purified Pab.

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  Flow cytometric analysis of 293 cells using Lysyl oxidase Antibody (Center) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 234~260 amino acids from the Center region of human Lysyl oxidase
• Specificity: This antibody recognizes Human Lysyl oxidase (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: lysyl oxidase
• Database Link:
  Entrez Gene 4015 Human
  UniProt ID P28300
• Background: LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression.
• Synonyms: LOX, Protein-lysine 6-oxidase, EC=1.4.3.13
• Note: Molecular Weight: 46944 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein