Placental lactogen (CSH1) (C-term) Rabbit Polyclonal Antibody
CAT#: AP51099PU-N
Placental lactogen (CSH1) (C-term) rabbit polyclonal antibody, Aff - Purified
Other products for "Placental lactogen"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 180-208 amino acids from the C-terminal region of human CSH1 |
Specificity | This antibody reacts to human CSH1. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide. |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 25020 Da |
Gene Name | chorionic somatomammotropin hormone 1 |
Database Link | |
Background | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq]. |
Synonyms | Choriomammotropin, CSH1, CSH2, CSA, HPL |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction |
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