Oct4 (POU5F1) (232-236) Rabbit Polyclonal Antibody
Other products for "Oct4"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1:1000. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around aa.232~236 derived from OCT-4 |
Specificity | This antibody detects endogenous level of total OCT-4 protein. |
Formulation | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity-chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | POU class 5 homeobox 1 |
Database Link | |
Background | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. |
Synonyms | POU5F1, OCT3, OCT4, OTF3, POU domain, class 5, transcription factor 1, Octamer-binding transcription factor 3, Oct-3, Oct-4 |
Note | Molecular weight: 45 kDa |
Reference Data | |
Protein Families | Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors |
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in shipping.