PIP5K2 alpha (PIP4K2A) (C-term) Rabbit Polyclonal Antibody
PIP5K2 alpha (PIP4K2A) (C-term) rabbit polyclonal antibody, Purified
Product Datasheet for 'AP14967PU-N'
|Recommend Dilution||ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Immunohistochemistry: 1/50 - 1/100.
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIP5K2A.|
|Specificity||This antibody reacts to PIP5K2 alpha.|
|Formulation||PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Gene Name||phosphatidylinositol-5-phosphate 4-kinase type 2 alpha|
|Background||Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.|
|Synonyms||PIP4KII-alpha, PIP5K2, PIP5KIII, Diphosphoinositide kinase 2-alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PtdIns(5)P-4-kinase isoform 2-alpha|
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