LOC100130809 Rabbit Polyclonal Antibody
Rabbit Polyclonal Anti-LOC100130809 Antibody, Aff - Purified
Product Datasheet for 'AP06716PU-N'
|Recommend Dilution||ELISA, IHC, WB|
|Immunogen||Synthetic peptide, corresponding to amino acids 50-100 of Human SRY|
|Formulation||PBS, pH 7.2|
|Purification||Affinity Chromatography using epitope-specific immunogen|
|Background||SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.