Acetylcholinesterase Rabbit Polyclonal Antibody

CAT#: AP05350PU-N

Acetylcholinesterase rabbit polyclonal antibody, Aff - Purified

USD 550.00

5 Days*

    • 1 ml

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Product Data
Applications ELISA, WB
Recommended Dilution ELISA: 1/6K-1/24K.
Western Blot: 1/10-1/50.
Reactivities Fish, Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Highly purified Acetylcholine Esterase from Electrophorus electricus.
Specificity This antibody reacts with Actylcholinesterase from Electrophorus electricus (electric eel).
Formulation Phosphate buffered saline containing 0.09% Sodium Azide as preservative.
State: Aff - Purified
State: Liquid purified IgG fraction.
Concentration lot specific
Purification Affinity chromatography on Protein G.
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
Synonyms AChE, Acetylcholine Esterase, Acetylcholine-Esterase
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.