Adarb1 Sheep Polyclonal Antibody

CAT#: AP05073PU-N

Adarb1 sheep polyclonal antibody, Aff - Purified

Product Images

Immunofluorescence staining of mouse anterior horns of spinal cord at 6 months, 15 months and 26 months of age. Antibody used at 1/100 dilution and visualized using Donkey anti-Sheep conjugated to Alexa 555 Dye (red color). The blue color is a fluorescent nuclear probe, TOPRO3. (Image modified from original in citation 1)

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western Blot: 1/1000.
  Positive Control: Rat Brain.
• Reactivities: Rat
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GST fusion protein containing aa 6-66 of the rat RED1 coding sequence
• Specificity: This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2).
• Formulation: State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Antigen Immunoaffiinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 80.7 kDa
• Gene Name: adenosine deaminase, RNA-specific, B1
• Database Link:
  Entrez Gene 25367 Rat
  UniProt ID P51400
• Background: RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.
• Synonyms: DRADA2, RED1, RNA-editing enzyme 1