Adarb1 Sheep Polyclonal Antibody
Adarb1 sheep polyclonal antibody, Aff - Purified
Product Datasheet for 'AP05073PU-N'
|Recommend Dilution||Western Blot: 1/1000.
Positive Control: Rat Brain.
|Immunogen||GST fusion protein containing aa 6-66 of the rat RED1 coding sequence|
|Specificity||This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2).|
|Formulation||State: Aff - Purified
State: Liquid purified Ig fraction
|Purification||Antigen Immunoaffiinity Chromatography|
|Predicted Protein Size||80.7 kDa|
|Background||RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.|
|Synonyms||DRADA2, RED1, RNA-editing enzyme 1|
|The use of this Antibodies has been cited in the following citations:|
Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.
,Yamashita T, Chai HL, Teramoto S, Tsuji S, Shimazaki K, Muramatsu S, Kwak S,
EMBO Mol Med 2013
,PubMed ID 24115583
Co-occurrence of TDP-43 mislocalization with reduced activity of an RNA editing enzyme, ADAR2, in aged mouse motor neurons.
,Hideyama T, Teramoto S, Hachiga K, Yamashita T, Kwak S,
PLoS ONE 2012
,PubMed ID 22916266
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