Cardiac Troponin I (TNNI3) (69-86) Goat Polyclonal Antibody

CAT#: AP00830PU-N

Cardiac Troponin I (TNNI3) (69-86) goat polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: Immunoassay: Use AP00830PU-N as a Detection Antibody in combination with AM05137PU-N as a Capture antibody in a Sandwich Immunoassay.
  Immunohistochemistry.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Highly purified Human Cardiac Troponin I
• Specificity: This antibody is specific for Human Cardiac Troponin I.
  Recognizes epitopes located in the 69-86 region of Troponin I.
  Cross reactivity with Human skeletal Troponin I is < 1% by ELISA.
• Formulation: 10mM Sodium Phosphate, 0.85% (w/v) Sodium Chloride, pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (>95% pure)
  Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Purification: Affinity purified with Solid Phase Human Cardiac Troponin I peptide 4
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: troponin I3, cardiac type
• Database Link:
  Entrez Gene 7137 Human
  UniProt ID P19429
• Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
• Synonyms: TNNI3, TNNC1