AMACR Mouse Monoclonal Antibody [Clone ID: 2A10F3]

CAT#: AM06190SU-N

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AMACR mouse monoclonal antibody, clone 2A10F3, Ascites



USD 470.00


Availability*
2 Weeks

Size
    • 100 ul


Product images

Specifications

Product Data
Clone Name 2A10F3
Applications IF, IHC, WB
Recommended Dilution ELISA: 1/10000.
Western Bloting:1/500 - 1/2000 .
Immunofluorescence: 1/200 - 1/1000. 
Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity Human, Mouse
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Purified recombinant fragment of human AMACR expressed in E. Coli.
Specificity Recognizes AMACR (alpha-methylacyl-CoA racemase).
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Background AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4); also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.
Synonyms Alpha-methylacyl-CoA racemase, P504S
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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