Her2 (ERBB2) Mouse Monoclonal Antibody [Clone ID: 9B9D8]

CAT#: AM06167SU-N

Her2 (ERBB2) mouse monoclonal antibody, clone 9B9D8, Ascites

Product Images

Western blot analysis using HER-2 antibody Cat.-No AM06167SU-N against truncated HER-2 recombinant protein.

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  Immunohistochemical analysis of paraffin-embedded human breast intraductal carcinama tissue (A) and breast infiltrating ductal carcinama tissue (B) showing membrane localization using HER-2 antibody Cat.-No AM06167SU-N with DAB staining.

Specifications

Product Data

• Clone Name: 9B9D8
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of HER-2 expressed in E. Coli.
• Specificity: Recognizes C-erbB-2 (HER-2/neu).
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: erb-b2 receptor tyrosine kinase 2
• Database Link:
  Entrez Gene 2064 Human
  UniProt ID P04626
• Background: The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis
• Synonyms: HER-2, NEU, p185erbB2, NGL, c-erbB-2, MNL19