Her2 (ERBB2) Mouse Monoclonal Antibody [Clone ID: 9B9D8]
Other products for "ERBB2"
Specifications
Product Data | |
Clone Name | 9B9D8 |
Applications | IHC, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of HER-2 expressed in E. Coli. |
Specificity | Recognizes C-erbB-2 (HER-2/neu). |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | erb-b2 receptor tyrosine kinase 2 |
Database Link | |
Background | The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis |
Synonyms | HER-2, NEU, p185erbB2, NGL, c-erbB-2, MNL19 |
Reference Data |
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