Ly86 Rat Monoclonal Antibody [Clone ID: MD113]
Ly86 rat monoclonal antibody, clone MD113, Purified
|Recommended Dilution||Flow cytometry: The typical starting working dilution is 1:50.
Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.
Cannot be used for Western blot and immunoprecipitation.
The monoclonal antibody MD113 reacts with mouse MD-1. The antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.
State: Liquid 0.2 μm filtered Ig fraction
Stabilizer: 0.1% bovine serum albumin
Preservative: 0.02% sodium azide
Store at 2 - 8 °C.
|Stability||Shelf life: one year from despatch.|
|Background||MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS.|
|Synonyms||Lymphocyte antigen 86, MD1|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.