NT5C1A (NM_032526) Human Recombinant Protein
SKU
TP324617
Purified recombinant protein of Homo sapiens 5'-nucleotidase, cytosolic IA (NT5C1A), 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 40.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_115915 |
| Locus ID | 84618 |
| UniProt ID | Q9BXI3 |
| Cytogenetics | 1p34.2 |
| RefSeq Size | 1107 |
| RefSeq ORF | 1104 |
| Synonyms | CN-I; CN-IA; CN1; CN1A; CNI |
| Summary | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 PubMed 11133996).supplied by OMIM, Mar 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Metabolic pathways, Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "NT5C1A" proteins (1)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH324617 | NT5C1A MS Standard C13 and N15-labeled recombinant protein (NP_115915) | 10 ug |
$3,360.00
|
|
Citations
Glycolytic flux control by drugging phosphoglycolate phosphatase
Jeanclos, Schlötzer, Hadamek et al
Nat Commun (2022) 13 (1), 6845 DOI: 10.1038/s41467-022-34228-2
Jeanclos, Schlötzer, Hadamek et al
Nat Commun (2022) 13 (1), 6845 DOI: 10.1038/s41467-022-34228-2
Cited by 12
AI Summary: OriGene contributed phosphatase plasmids—specifically murine LHPP (MC211738), LPIN1 (MC204460), MDP1 (MR201315), and NANP/HDHD4 (MR203153)—which were used in this study to investigate the selectivity of the PGP inhibitor CP1 and to compare activities among related phosphatases.
Snippet: (CP3) were from ChemDiv. Compounds 1D, 1E and 1F were from Ambinter. Phosphatase plasmids and commercially available phosphatases The following phosphatase constructs (in pCMV6) were purchased from Origene: murine LHPP (NM_029609;catalog #MC211738), murine LPIN1, transcript variant 2 (NM_015763, #MC204460), murine MDP1 (NM_023397, #MR201315), murine NANP/HDHD4 (NM_026086, #MR203153), murine NT5
Anti-cN-1A autoantibodies are absent in juvenile dermatomyositis
Rietveld, Wienke, Visser et al
Arthritis Rheumatol (2021)
Rietveld, Wienke, Visser et al
Arthritis Rheumatol (2021)
Cited by 6
AI Summary: OriGene's recombinant cN-1A protein (TP324617) was used in an in-house ELISA to assess anti-cN-1A autoantibody reactivity in the independent British cohort, helping demonstrate the absence of these autoantibodies in juvenile dermatomyositis patients.
HLA-DRB1 allele and autoantibody profiles in Japanese patients with inclusion body myositis
Oyama, Ohnuki, Inoue et al
PLoS ONE (2020) 15 (8), e0237890 DOI: 10.1371/journal.pone.0237890
Oyama, Ohnuki, Inoue et al
PLoS ONE (2020) 15 (8), e0237890 DOI: 10.1371/journal.pone.0237890
Cited by 14
AI Summary: OriGene's recombinant cN1A protein was used in ELISA assays to detect anti-cN1A autoantibodies in Japanese patients with inclusion body myositis, aiding the study of autoantibody profiles.
Snippet: ELISAs of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and anti-cN1A antibodies were performed using C-terminal recombinant HMGCR protein (Sigma) and recombinant cN1A protein (Origene, Rockville, MD) [18]. HLA-DRB1 genotyping Cached;- ELISAs of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and anti-cN1A antibodies were performed using C-terminal recombinant...
Anti-NT5c1A Autoantibodies as Biomarkers in Inclusion Body Myositis
Amlani, Choi, Tarnopolsky et al
Front Immunol (2019) 10, 745 DOI: 10.3389/fimmu.2019.00745
Amlani, Choi, Tarnopolsky et al
Front Immunol (2019) 10, 745 DOI: 10.3389/fimmu.2019.00745
AI Summary: OriGene contributed to this study by providing the full-length human recombinant NT5c1A protein (Cat# specified as OriGene, Rockville, MD), which was used in the addressable laser bead immunoassay (ALBIA) to detect anti-NT5c1A autoantibodies in patient sera.
Snippet: Autoantibody Testing. Coupling of Addressable Laser Beads. Autoantibody testing was performed at Mitogen Advanced Diagnostics Laboratory. Antibodies to NT5c1A were detected by ALBIA using a full-length human recombinant protein (Origene, Rockville, MD: Cat
Showing 1-4 of 4 papers.
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