Ercc3 Mouse Gene Knockout Kit (CRISPR)
Ercc3 - mouse gene knockout kit via CRISPRchange donor?
KN305323G1, Ercc3 gRNA vector 1 in pCas-Guide vector,
KN305323G2, Ercc3 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||BC016595, BC026575, NM_133658|
|Synonyms||BTF2 p89; Ercc-3; XPB|
|Summary||ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. [UniProtKB/Swiss-Prot Function]|
|Gene Expression Resources|
"Ercc3" in other Product Lines
Related Products (2)
Mouse monoclonal anti-GAPDH antibody, clone 2D9, Loading, clone OTI2D9 (formerly 2D9)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control