FGF20 Human Gene Knockout Kit (CRISPR)

CAT#: KN214423

FGF20 - human gene knockout kit via CRISPR

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USD 1,290


Availability*
4 Weeks

Size
    • 1 kit

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Specifications

Product Data
Symbol FGF20
Locus ID 26281
Kit Components

KN214423G1, FGF20 gRNA vector 1 in pCas-Guide vector,

KN214423G2, FGF20 gRNA vector 2 in pCas-Guide vector,

KN214423-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_019851
Synonyms FGF-20; RHDA2
Summary The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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