RNF144A Human Gene Knockout Kit (CRISPR)
RNF144A - human gene knockout kit via CRISPRchange donor?
KN208254G1, RNF144A gRNA vector 1 in pCas-Guide vector,
KN208254G2, RNF144A gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_014746, XM_005246200, XM_005246202, XM_017005396, XM_017005397, XM_017005398, XM_017005399, XM_017005400, XM_017005401, XM_017005402, XM_017005403, XM_017005404, XR_001739082|
|Summary||This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017]|
|Gene Expression Resources|
"RNF144A" in other Product Lines
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