ZC3HAV1 Human Gene Knockout Kit (CRISPR)
ZC3HAV1 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN208070G1, ZC3HAV1 gRNA vector 1 in pCas-Guide vector
KN208070G2, ZC3HAV1 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||AK055851, NM_020119, NM_024625, XM_005250501, XM_011516412|
|Synonyms||ARTD13; FLB6421; PARP13; ZAP; ZC3H2; ZC3HDC2|
|Summary||This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. [provided by RefSeq, Jul 2008].|
|Gene Expression Resources|