IFI30 Human Gene Knockout Kit (CRISPR)
IFI30 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN205877G1, IFI30 gRNA vector 1 in pCas-Guide vector
KN205877G2, IFI30 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||GILT; IFI-30; IP-30; IP30|
|Summary||The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008].|
|Gene Expression Resources|