Mouse Atp6ap2 activation kit by CRISPRa

CAT#: GA208541

Atp6ap2 CRISPRa kit - CRISPR gene activation of mouse ATPase, H+ transporting, lysosomal accessory protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Atp6ap2
• Locus ID: 70495
• Kit Components:

  GA208541G1, Atp6ap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208541G2, Atp6ap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208541G3, Atp6ap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_027439
• UniProt ID: Q9CYN9
• Synonyms: (P)RR; 5730403E06Rik; APT6M8-9; Atp6ip2; ATP6M8-9; M8-9; PRR
• Summary: Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).[UniProtKB/Swiss-Prot Function]