Human CARD14 activation kit by CRISPRa

CAT#: GA112364

CARD14 CRISPRa kit - CRISPR gene activation of human caspase recruitment domain family member 14

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CARD14
• Locus ID: 79092
• Kit Components:

  GA112364G1, CARD14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112364G2, CARD14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112364G3, CARD14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001257970, NM_024110, NM_052819, NR_047566, NM_001366385
• UniProt ID: Q9BXL6
• Synonyms: BIMP2; CARMA2; PRP; PSORS2; PSS1
• Summary: This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]