Human STK39 activation kit by CRISPRa

CAT#: GA109139

STK39 CRISPRa kit - CRISPR gene activation of human serine/threonine kinase 39

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: STK39
• Locus ID: 27347
• Kit Components:

  GA109139G1, STK39 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109139G2, STK39 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109139G3, STK39 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013233
• UniProt ID: Q9UEW8
• Synonyms: DCHT; PASK; SPAK
• Summary: This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]