Human GPR161 activation kit by CRISPRa

CAT#: GA108306

GPR161 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 161

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GPR161
• Locus ID: 23432
• Kit Components:

  GA108306G1, GPR161 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108306G2, GPR161 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108306G3, GPR161 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001267609, NM_001267610, NM_001267611, NM_001267612, NM_001267613, NM_001267614, NM_007369, NM_153832, NM_001349632, NM_001349633, NM_001349634, NM_001349635
• UniProt ID: Q8N6U8
• Synonyms: RE2
• Summary: The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]