Human IGF2BP1 activation kit by CRISPRa

CAT#: GA107292

IGF2BP1 CRISPRa kit - CRISPR gene activation of human insulin like growth factor 2 mRNA binding protein 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: IGF2BP1
• Locus ID: 10642
• Kit Components:

  GA107292G1, IGF2BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107292G2, IGF2BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107292G3, IGF2BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001160423, NM_006546
• UniProt ID: Q9NZI8
• Synonyms: CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1
• Summary: This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]