Human TTF2 activation kit by CRISPRa

CAT#: GA105589

TTF2 CRISPRa kit - CRISPR gene activation of human transcription termination factor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TTF2
• Locus ID: 8458
• Kit Components:

  GA105589G1, TTF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105589G2, TTF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105589G3, TTF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003594
• UniProt ID: Q9UNY4
• Synonyms: HuF2; ZGRF6
• Summary: This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]