Human PFKP activation kit by CRISPRa

CAT#: GA103504

PFKP CRISPRa kit - CRISPR gene activation of human phosphofructokinase, platelet

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PFKP
• Locus ID: 5214
• Kit Components:

  GA103504G1, PFKP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103504G2, PFKP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103504G3, PFKP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242339, NM_002627, NM_001323067, NM_001323068, NM_001323069, NM_001323070, NM_001323071, NM_001323072, NM_001323073, NM_001323074, NM_001345944
• UniProt ID: Q01813
• Synonyms: ATP-PFK; PFK-C; PFK-P; PFKF
• Summary: This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]