Human LGALS3BP activation kit by CRISPRa

CAT#: GA102684

LGALS3BP CRISPRa kit - CRISPR gene activation of human galectin 3 binding protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: LGALS3BP
• Locus ID: 3959
• Kit Components:

  GA102684G1, LGALS3BP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102684G2, LGALS3BP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102684G3, LGALS3BP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005567
• UniProt ID: Q08380
• Synonyms: 90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B
• Summary: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]