DOCK8 (NM_203447) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222789L1V

Lenti ORF particles, DOCK8 (Myc-DDK tagged) - Human dedicator of cytokinesis 8 (DOCK8), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: DOCK8
• Synonyms: HEL-205; MRD2; ZIR8
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_203447
• ORF Size: 6093 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222789).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_203447.1, NP_982272.1
• RefSeq Size: 7257 bp
• RefSeq ORF: 6300 bp
• Locus ID: 81704
• UniProt ID: Q8NF50
• Cytogenetics: 9p24.3
• MW: 238.3 kDa
• Gene Summary: This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]