FATP2 (SLC27A2) (NM_003645) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221033L4V

Lenti ORF particles, SLC27A2 (mGFP-tagged) - Human solute carrier family 27 (fatty acid transporter), member 2 (SLC27A2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SLC27A2
• Synonyms: ACSVL1; FACVL1; FATP2; hFACVL1; HsT17226; VLACS; VLCS
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_003645
• ORF Size: 1860 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221033).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003645.2
• RefSeq Size: 2343 bp
• RefSeq ORF: 1863 bp
• Locus ID: 11001
• UniProt ID: O14975
• Cytogenetics: 15q21.2
• Domains: AMP-binding
• Protein Families: Transmembrane
• Protein Pathways: PPAR signaling pathway
• MW: 70.1 kDa
• Gene Summary: The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]