TRPC4 (NM_016179) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218941L3V

Lenti ORF particles, TRPC4 (Myc-DDK tagged) - Human transient receptor potential cation channel, subfamily C, member 4 (TRPC4), transcript variant alpha, 200ul, >10^7 TU/mL

Product Images

RC218941L3 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC218941L3V particle to overexpress human TRPC4-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TRPC4
• Synonyms: HTRP-4; HTRP4; TRP4
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_016179
• ORF Size: 2931 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218941).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_016179.1
• RefSeq Size: 3440 bp
• RefSeq ORF: 2934 bp
• Locus ID: 7223
• UniProt ID: Q9UBN4
• Cytogenetics: 13q13.3
• Domains: ANK, ion_trans
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• MW: 111.9 kDa
• Gene Summary: This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]