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KIAA1199 (CEMIP) (NM_018689) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC215547L3V
- LentiORF®
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Lenti ORF particles, KIAA1199 (Myc-DDK-tagged)-Human KIAA1199 (KIAA1199), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50
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USD 365.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | Myc-DDK |
| Symbol | CEMIP |
| Synonyms | CCSP1; HYBID; KIAA1199; TMEM2L |
| Mammalian Cell Selection | Puromycin |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_018689 |
| ORF Size | 4083 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC215547).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018689.1 |
| RefSeq Size | 7080 bp |
| RefSeq ORF | 4086 bp |
| Locus ID | 57214 |
| UniProt ID | Q8WUJ3 |
| Cytogenetics | 15q25.1 |
| MW | 153 kDa |
| Gene Summary | Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.[UniProtKB/Swiss-Prot Function] |
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