SRP72 (NM_006947) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214727L2V

Lenti ORF particles, SRP72 (mGFP-tagged) - Human signal recognition particle 72kDa (SRP72), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SRP72
• Synonyms: BMFF; BMFS1; HEL103
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_006947
• ORF Size: 2013 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214727).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006947.2
• RefSeq Size: 3852 bp
• RefSeq ORF: 2016 bp
• Locus ID: 6731
• UniProt ID: O76094
• Cytogenetics: 4q12
• Domains: TPR
• Protein Pathways: Protein export
• MW: 74.4 kDa
• Gene Summary: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]