GCKR (NM_001486) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214230L3V

Lenti ORF particles, GCKR (Myc-DDK tagged) - Human glucokinase (hexokinase 4) regulator (GCKR), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GCKR
• Synonyms: FGQTL5; GKRP
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001486
• ORF Size: 1875 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214230).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001486.2
• RefSeq Size: 2197 bp
• RefSeq ORF: 1878 bp
• Locus ID: 2646
• UniProt ID: Q14397
• Cytogenetics: 2p23.3
• Domains: SIS
• MW: 69.1 kDa
• Gene Summary: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]