TRPC6 (NM_004621) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210783L2V

Lenti ORF particles, TRPC6 (mGFP-tagged) - Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TRPC6
• Synonyms: FSGS2; TRP6
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_004621
• ORF Size: 2793 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210783).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004621.3
• RefSeq Size: 4564 bp
• RefSeq ORF: 2796 bp
• Locus ID: 7225
• UniProt ID: Q9Y210
• Cytogenetics: 11q22.1
• Domains: ANK, ion_trans
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• MW: 106.1 kDa
• Gene Summary: The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]