KAT2B (NM_003884) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209821L4V

Lenti ORF particles, KAT2B (mGFP-tagged) - Human K(lysine) acetyltransferase 2B (KAT2B), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: KAT2B
• Synonyms: CAF; P/CAF; PCAF
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_003884
• ORF Size: 2496 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209821).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003884.3
• RefSeq Size: 4838 bp
• RefSeq ORF: 2499 bp
• Locus ID: 8850
• UniProt ID: Q92831
• Cytogenetics: 3p24.3
• Domains: Acetyltransf, BROMO
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Notch signaling pathway
• MW: 92.8 kDa
• Gene Summary: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]