NSMAF (NM_003580) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207925L4V

Lenti ORF particles, NSMAF (mGFP-tagged) - Human neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: NSMAF
• Synonyms: FAN; GRAMD5
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_003580
• ORF Size: 2751 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207925).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003580.2, NP_003571.2
• RefSeq Size: 3582 bp
• RefSeq ORF: 2754 bp
• Locus ID: 8439
• UniProt ID: Q92636
• Cytogenetics: 8q12.1
• Domains: Beach, WD40, GRAM
• Protein Families: Druggable Genome
• MW: 104.4 kDa
• Gene Summary: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]