Thymine DNA glycosylase (TDG) (NM_003211) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207113L4V

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  • LentiORF®

Lenti ORF particles, TDG (mGFP-tagged) - Human thymine-DNA glycosylase (TDG), 200ul, >10^7 TU/mL



USD 1,007.00

3 Weeks*

Size
    • 200 ul

Product images

Frequently bought together (2)
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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol TDG
Synonyms hTDG
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_003211
ORF Size 1230 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC207113).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_003211.3
RefSeq Size 3251 bp
RefSeq ORF 1233 bp
Locus ID 6996
UniProt ID Q13569
Cytogenetics 12q23.3
Domains UDG
Protein Families Druggable Genome
Protein Pathways Base excision repair
MW 46 kDa
Gene Summary The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.