ALS (IGFALS) (NM_004970) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206542L3V

Lenti ORF particles, IGFALS (Myc-DDK tagged) - Human insulin-like growth factor binding protein, acid labile subunit (IGFALS), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ALS
• Synonyms: ACLSD; ALS
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_004970
• ORF Size: 1815 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206542).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004970.1
• RefSeq Size: 2168 bp
• RefSeq ORF: 1818 bp
• Locus ID: 3483
• UniProt ID: P35858
• Cytogenetics: 16p13.3
• Protein Families: Druggable Genome, Secreted Protein
• MW: 66.1 kDa
• Gene Summary: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]