CLN6 (NM_017882) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201904L3V

Lenti ORF particles, CLN6 (Myc-DDK tagged) - Human ceroid-lipofuscinosis, neuronal 6, late infantile, variant (CLN6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CLN6
• Synonyms: CLN4A; HsT18960; nclf
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_017882
• ORF Size: 933 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201904).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017882.1
• RefSeq Size: 2258 bp
• RefSeq ORF: 936 bp
• Locus ID: 54982
• UniProt ID: Q9NWW5
• Cytogenetics: 15q23
• Protein Families: Transmembrane
• MW: 35.9 kDa
• Gene Summary: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]