COPS6 (NM_006833) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200252L3V

Lenti ORF particles, COPS6 (Myc-DDK tagged) - Human COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) (COPS6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: COPS6
• Synonyms: CSN6; MOV34-34KD
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_006833
• ORF Size: 981 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200252).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006833.4
• RefSeq Size: 1441 bp
• RefSeq ORF: 984 bp
• Locus ID: 10980
• UniProt ID: Q7L5N1
• Cytogenetics: 7q22.1
• Domains: JAB_MPN
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 36.2 kDa
• Gene Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]