Il23r (NM_144548) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227592L3V

Lenti ORF particles, Il23r (Myc-DDK-tagged) - Mouse interleukin 23 receptor (Il23r), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Il23r
• Synonyms: IL-23R
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_144548
• ORF Size: 1977 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227592).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_144548.1, NP_653131.2
• RefSeq Size: 2488 bp
• RefSeq ORF: 1980 bp
• Locus ID: 209590
• UniProt ID: Q8K4B4
• Cytogenetics: 6 C1
• Gene Summary: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity).[UniProtKB/Swiss-Prot Function]