Il23r (NM_144548) Mouse Untagged Clone

CAT#: MC220198

Il23r (untagged) - Mouse interleukin 23 receptor (Il23r), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Il23r
• Synonyms: IL-23R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220198 representing NM_144548
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAAAGAGAGAGAGAAATGAGAGGCTTCTACTACATTTGGGACATGAGTCACCTCACACTTCAGCTGC
  ATGTGGTGATAGCCCTTTATGTGCTCTTCAGATGGTGTCACGGAGGAATCACAAGTATAAACTGCTCTGG
  TGACATGTGGGTTGAGCCTGGTGAAATTTTTCAGATGGGCATGAATGTTTCTATATATTGCCAAGAAGCC
  CTTAAGCACTGCCGACCAAGGAATCTTTACTTTTATAAAAATGGCTTCAAAGAAGAATTTGATATCACAA
  GGATTAATAGAACAACAGCTCGGATTTGGTATAAAGGCTTTTCGGAACCTCATGCCTATATGCATTGCAC
  TGCTGAATGTCCTGGTCATTTTCAAGAGACACTGATTTGTGGGAAAGACATTTCCTCTGGACATCCACCG
  GATGCCCCCAGCAATCTGACATGTGTCATTTATGAATACTCAGGCAACATGACATGCACCTGGAACACTG
  GGAAGCCTACCTACATAGATACCAAGTATATTGTGCATGTGAAGAGTTTGGAGACAGAAGAAGAACAACA
  ATATCTTGCCTCAAGCTATGTTAAGATCTCCACTGACTCACTGCAAGGCAGCAGGAAGTATTTGGTATGG
  GTCCAAGCTGTCAATTCCCTAGGCATGGAGAACTCACAACAACTACACGTCCATCTGGATGATATAGTGA
  TACCTTCTGCGTCCATCATTTCCAGGGCTGAGACTACAAACGATACTGTACCCAAGACCATAGTTTACTG
  GAAAAGCAAAACTATGATTGAGAAAGTATTCTGTGAGATGAGATACAAAACAACAACAAACCAAACGTGG
  AGTGTTAAAGAATTTGACGCCAATTTCACATATGTACAGCAGTCAGAATTCTACCTGGAGCCAGACAGCA
  AGTATGTATTTCAAGTGCGATGTCAAGAAACTGGTAAAAGAAACTGGCAGCCTTGGAGTTCCCCCTTTGT
  CCACCAAACTTCCCAAGAAACTGGTAAAAGAAACTGGCAGCCTTGGAGTTCCCCCTTTGTCCACCAAACT
  TCCCAGACAGTTTCCCAGGTTACAGCAAAATCATCCCACGAACCTCAGAAGATGGAGATGCTCAGTGCTA
  CAATCTTCAGAGGACATCCTGCTTCAGGTAATCATCAAGACATTGGACTTTTGTCGGGAATGGTCTTCTT
  GGCCATCATGTTGCCGATTTTTTCTCTGATTGGGATATTTAACAGATCACTTCGAATAGGAATTAAAAGA
  AAAGTTTTACTGATGATCCCAAAGTGGCTTTATGAAGATATTCCTAATATGGAAAATAGCAATGTTGCAA
  AATTATTACAGGAAAAAAGTGTATTTGAGAATGATAATGCCAGTGAGCAGGCCCTGTATGTGGATCCTGT
  CCTTACAGAGATAAGTGAAATCTCTCCCCTGGAACACAAACCCACAGATTACAAAGAAGAAAGGCTCACA
  GGACTCCTTGAGACAAGAGACTGTCCTCTAGGAATGTTGTCTACCAGTTCTTCTGTTGTGTATATTCCTG
  ACCTCAACACTGGATACAAACCCCAGGTTTCAAATGTTCCTCCTGGAGGAAACCTTTTCATTAACAGAGA
  TGAAAGAGACCCTACATCCCTTGAGACCACAGATGACCACTTTGCCAGATTGAAAACATATCCCAACTTC
  CAATTTTCTGCTTCAAGTATGGCTTTACTAAACAAAACACTAATTCTTGATGAATTGTGCCTCGTTTTAA
  ATCAAGGAGAATTCAATTCTCTTGACATAAAAAACTCAAGACAGGAGGAAACCAGCATCGTTTTGCAAAG
  TGACTCACCCAGTGAAACTATCCCAGCGCAGACTCTGTTGTCTGATGAATTTGTCTCCTGTTTGGCAATT
  GGGAATGAAGACTTGCCATCTATTAATTCTTACTTTCCACAGAACGTTTTGGAAAGCCATTTCAGTAGAA
  TTTCACTCTTCCAAAAGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_144548
• Insert Size: 1980 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_144548.1, NP_653131.2
• RefSeq Size: 2488 bp
• RefSeq ORF: 1980 bp
• Locus ID: 209590
• UniProt ID: Q8K4B4
• Cytogenetics: 6 C1
• Gene Summary: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity).[UniProtKB/Swiss-Prot Function]