Ntn1 (NM_008744) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR223704L3V

  • LentiORF®

Lenti ORF particles, Ntn1 (Myc-DDK-tagged) - Mouse netrin 1 (Ntn1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro



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USD 1,393.00

7 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Symbol Ntn1
Synonyms AI561871; BC019633; Netrin-1
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_008744
ORF Size 1812 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR223704).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_008744.2, NP_032770.2
RefSeq Size 5757 bp
RefSeq ORF 1815 bp
Locus ID 18208
UniProt ID O09118
Cytogenetics 11 B3
Gene Summary Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed:28483977). Involved in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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