Wnt3 (NM_009521) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR222492L3V

Lenti ORF particles, Wnt3 (Myc-DDK-tagged) - Mouse wingless-related MMTV integration site 3 (Wnt3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Wnt3
• Synonyms: Int-4; Wnt-3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_009521
• ORF Size: 1065 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR222492).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009521.2, NP_033547.1
• RefSeq Size: 3115 bp
• RefSeq ORF: 1068 bp
• Locus ID: 22415
• UniProt ID: P17553
• Cytogenetics: 11 67.5 cM
• Gene Summary: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis (PubMed:10431240). Required for normal formation of the apical ectodermal ridge and for normal embryonic limb development (PubMed:12569130).[UniProtKB/Swiss-Prot Function]